Toshiaki Tanaka*, Koji Moriya, Makoto Tsunenaga, Takayo Yanagawa, Hiromi Morita, Takashi Minowa, Yoh-ichi Tagawa, Nobutaka Hanagata, Yutaka Inagaki, and Toshiyuki Ikoma.Visualized procollagen Ia1 demonstrates the intracellular processing of propeptides.Life Science Alliance 5(5): e202101060, 2022.
K. Moriya, M. Tamai, T. Koga, T. Tanaka, Y. Tagawa. Acetaminophen-induced hepatotoxicity of cultured hepatocytes depends on timing of isolation from light-cycle controlled mice. Genes to Cells25, 257-269, 2020.
K. Kawaguchi, A. Endo, T. Fukushima, Y. Madoka, T. Tanaka, M. Komada. Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion. Biochemical and Biophysical Research Communications499, 635-641, 2018.
Y. Satou, K. Minami, E. Hosono, H. Okada, Y. Yasuoka, T. Shibano, T. Tanaka, M. Taira. Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo. Development145, dev159640, 2018.
T. Tanaka*, H. Ochi, S. Takahashi, N. Ueno, M. Taira. Genes coding for Cyclin-dependent Kinase Inhibitors are Fragile in Xenopus. Developmental Biology426, 291-300, 2017.
K. Kawaguchi, K. Uo, T. Tanaka, M. Komada. Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25. Scientific Reports7, 45037, 2017.
A. M. Session, Y. Uno, T. Kwon,, T.Tanaka et al.Genome evolution in the allotetraploid frog Xenopus laevis. Nature538, 336–343, 2016.
H. Tanno, T. Shigematsu, S. Nishikawa, A. Hayakawa, K. Denda, T. Tanaka, M. Komada. Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37. Journal of Biological Chemistry289, 2415-2423, 2014.
X. Li, Y. Bian, Y. Takizawa, T. Hashiomoto, N. Kitamura, T. Ikoma, J. Tanaka, Y. Inagaki, M. Komada, T. Tanaka*. ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression. Molecular Cancer Research11 (11),1437-1447, 2013.
M. Hara, Y. Abe, T. Tanaka, T. Yamamoto, E. Okumura, T. Kishimoto. Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase promoting factor. Nature Communications3, 1059, 2012.
R. Igarashi, T. Sakai, H. Hara, T. Tenno, T. Tanaka, H. Tochio, M.Shirakawa. Distance determination in proteins inside Xenopus laevis oocytes by double electron-electron resonance experiments. Journal of the American Chemical Society132, 8228-8229, 2010.
K. Ushio, T. Hashimoto, N. Kitamura. T. Tanaka*. Id1 is down-regulated by hepatocyte growth factor via ERK-dependent and –independent signaling pathways, leading to increased expression of p16INK4a in hepatoma cells. Molecular Cancer Research7, 1179-1188, 2009.
E. Shirako, N. Hirayama, Y. Tsukada, T. Tanaka*, N. Kitamura*. Up-regulation of p21CIP1 expression mediated by ERK-dependent and –independent pathways contributes to hepatocyte growth factor induced inhibition of HepG2 hepatoma cell proliferation. Journal of Cellular Biochemistry104, 176-188, 2008.
A. Kondo, N. Hirayama, Y. Sugito, M. Shono, T. Tanaka, N. Kitamura. Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation. Journal of Biological Chemistry283, 1428-1436, 2008.
J. Han, Y. Tsukada, E. Hara, N. Kitamura, T. Tanaka*. Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells. Journal of Biological Chemistry280, 31548-31556, 2005.
T. Tanaka, M. Kubota, K. Shinohara, K. Yasuda, J-Y. Kato. In vivo analysis of the cyclin D1 promoter during early embryogenesis in Xenopus. Cell Structure and Function28, 165-177, 2003. Picked in Cover Image.
T. Tanaka, T. Ono, N. Kitamura, J-Y. Kato. Dominant negative E2F inhibits progression of the cell cycle after the midblastula transition in Xenopus. Cell Structure and Function28, 515-522, 2003.
@京都大学&奈良科学技術大学院大学
K. Tomoda, Y. Kubota, Y. Arata, S. Mori, M. Maeda, T. Tanaka, N. Yoneda-Kato, J-Y. Kato. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. Journal of Biological Chemistry277, 2302-2310, 2002.
K. Kurokawa, T. Tanaka, J-Y. Kato. p19ARF prevents G1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts. Oncogene18, 2718-2727, 1999.
E. Akamatsu, T. Tanaka, J-Y. Kato. Transcription factor E2F and Cyclin E-Cdk2 complex cooperate to induce chromosomal DNA replication in Xenopus oocytes. Journal of Biological Chemistry273, 16494-16500, 1998.
K. Itahana, T. Tanaka, Y. Morikazu, S. Komatsu, N. Ishida, T. Takeya. Isolation and characterization of a novel connexin gene, Cx-60, in porcine ovarian follicles. Endocrinology139, 320-329, 1998.
T. Tanaka, K. Itahana, N. Ando, T. Takeya, E. Sato. Expression of prostatic secretory protein (PSP)-like protein in porcine corpus luteum: Isolation and characterization of a new gene encoding PSP94-like protein. Molecular Reproduction and Development42, 149-156, 1995.
T. Tanaka, N. Andoh, T. Takeya, E. Sato. Differential screening of ovarian cDNA libraries detected the expression of the porcine collagenase inhibitor gene in functional corpora lutea. Molecular and Cellular Endocrinology83, 65-71, 1992.
@名古屋大学
Y. Takahashi, H. Kuroda, T. Tanaka, Y. Machida, I. Takebe, T. Nagata. Isolation of an auxin-regulated gene cDNA expressed during the transition from G0 to S phase in tabacco mesophyl protoplasts. Proceedings of the National Academy of Sciences of the USA86, 9279-9283, 1989.
J-Y.Kato, K.Tomoda, Y.Arata, T.Tanaka, N.Yoneda-Kato.
“CDK inhibitors: Genes and Drugs.”
Tumor Suppressing Virus, Genes, and Drugs: Innovative Cancer Therapy Approaches. (H. Maruta ed.)
pp. 123-143 (Chapter 6), 1/Nov, 2001. Academic Press, San Diego.
講演
GTIE DEMO day FY2022「Applied Biomatrix 起業プロジェクト」 田中利明 2023年3月3日 @渋谷スクランブルスクエア
https://gtie-demo-day-fy2022.peatix.com/
GTIE プレデモデイシンポジウム 招待講演 「可視化 I 型コラーゲンの社会実装」 田中利明 2022年11月30日 @慶應大 三田キャンパス北館ホールもしくはオンラインhttps://peatix.com/event/3404834
第12回化粧品開発展 アカデミックフォーラム 「可視化I型コラーゲンによる分泌評価と成分/薬剤スクリーニング」
“Visualized type I Collagen enables evaluation of the secretion and screening of regulatory factors” 田中利明 2022年01月12日(会期12-14日) @東京ビッグサイト
BioJapan 2019
「可視化技術による I 型コラーゲン生合成のライブイメージング」
(Visualization of processing and secretion of type I collagen by live imaging) 田中利明
2019 年 10月10日(会期9-11 日) @パシフィコ横浜
International Symposium on Genome Science.
“What we can do with over 300 billion bases of RNA-seq data: The case of Xenopus laevis genome project.”
T. Kwon, S. Takahashi, T. Tanaka, H. Noguchi, A. Toyoda., A. Fujiyama, Y. Suzuki, N. Ueno, M. Taira, J. B. Wallingford, E. M. Marcotte. 2013年1月9日 @The University of Tokyo, Ito International Research Center, Japan.
STAC-12 (The 12th International Conference on the Science and Technology for Advanced Ceramics, 国際学会)口頭発表
“Synthesis and characterization of Hydroxyapatite Hollow Nanoparticles for DNA Delivery Vehicles.”
中川泰宏、錦織桜子、守矢恒司、田中利明、生駒俊之
2021年7月6日~8日 @オンライン開催
29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine.
Bioceramics 29 (Poster)
“Hollow mesoporous silica particles with large pores for encapsulation of drugs.”
M. Iwatsuka, T. Ikoma, T. Tanaka.
2017 年 8月25-27日 @Touoluse, France.